Numera Cas: 144701-48-4 Fuafuaga Molecular: C33H30N4O2

Fa'amatalaga Puupuu:

Numera Cas: 144701-48-4
Igoa Vailaau:
Fuafua mole:C33H30N4O2

Synonyms:MICARDIS;TU-199;Telmisaran;TIMISHATAN;2-(4-{[4-Methyl-6-(1-Methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1 ,3-benzodiazol-1-yl]Methyl}phenyl)benzoic acid;4′[(1,4′-Dimethyl-2′-propyl[2,6′-bi-1H-benzimidazol]-1′-yl)methyl ][1,1′-biphenyl]-2-carboxylic acid, BIBR 277; PRITOR; BIBR 277; misartan; BIBR 277SE

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Fa'amatalaga Oloa

Faailoga o oloa

Oloa Fa'amatalaga

Lisi Lisi	261-263°C
Malosi	1.16 (fa'atatau fa'atatau)
taimi e teu ai	Atemosifia inert, Temperature Room 2-8°C
solubility	DMSO: >5 mg/mL ile 60 °C
gaioiga fa'apitoa	N/A
Fa'aaliga	Pa'e Pa'epa'e Malosi
Mama	≥98%

Fa'amatalaga

na faʻalauiloaina i le US mo togafitiga o le toto maualuga.E mafai ona saunia i laasaga e valu e amata ile methyl 4-amino-3-methyl benzoate;o le taamilosaga muamua ma le lona lua i totonu o se mama benzimidazole e tupu i laasaga 4 ma le 6.poloka le gaioiga a le angiotensin II (Ang II), o le mole o le faʻaogaina muamua o le renin-angiotensin-aldosterone system (RAAS).O le lona ono lea o lenei vasega o 《sartans》 e fa'atauina pe a mae'a le ta'imua o Losartan.O lona aafiaga umi (24h afa-ola) e mafai ona avea ma se eseesega tele ma isi faʻalavelave angiotensin II.E le pei o isi vailaʻau i lenei vaega, o lana gaioiga e le faʻalagolago i le suiga i se metabolite malosi, o le 1-O-acylglucuronide o le metabolite autu lea e maua i tagata. angiotensin II a'o leai se feso'ota'iga mo le AT2 subtypes po'o isi fa'afofoga o lo'o a'afia i le fa'atonuga o le cardiovascular.I le tele o su'esu'ega fa'afoma'i, fa'atasi i aso ta'itasi, na maua ai a'afiaga e fa'aitiitia ai le mamafa o le toto ma fa'aitiitia ai a'afiaga (aemaise o le tale e feso'ota'i ma togafitiga fa'atasi ma ACE inhibitors i tagata matutua).