Numera Cas: 21187-98-4 Fuafuaga Molecular

Fa'amatalaga Puupuu:

Numera Cas: 21187-98-4

Igoa Vailaau:

Fuafua mole: C15H21N3O3S

upu uiga tutusa:BP;)-4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;1-(hexahydrocyclopenta(c)pyrrol-2(1h )-yl)-3-(p-tolylsulfonyl)-ure;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)urea;benzenesulfonamide,n-(((hexahydrocyclopenta() c)pyrrol-2(1h)-yl)amino)carbonyl;n-(4-methylbenzenesulfonyl)-n'-(3-azabicyclo(3.3.0)oct-3-yl)urea;Tetrabenzyl Voglibose HCl

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Fa'amatalaga Oloa

Faailoga o oloa

Oloa Fa'amatalaga

Lisi Lisi	163-169 °C
Malosi	1.2205 (fa'atatau fa'atatau)
taimi e teu ai	Atemosifia inert, Temperature Room 2-8°C
solubility	methylene chloride: solu
gaioiga fa'apitoa	N/A
Fa'aaliga	Pa'e Pa'epa'e Malosi
Mama	≥98%

Fa'amatalaga

ose vaila'au antihyperglycemic oral e fa'aaogaina mo le togafitia o le ma'isuka ituaiga II.E a'afia i le vasega sulfonylurea o insulin secretagogues, lea e fa'aosofia ai sela β o le pancreas e fa'asa'oloto le inisalini.e fusifusia i le β cell sulfonyl urea receptor (SUR1), faʻapipiʻi atili ai le ATP maʻaleʻale ala o le potassium.O le mea lea, o le paʻu o le potassium e faʻaitiitia tele, ma mafua ai le depolarization o sela β.Ona matala lea o alalaupapa calcium-faalagolago i le β cell, e mafua ai le faʻagaoioia o le calmodulin, lea e oʻo atu ai i le exocytosis o le inisalini o loʻo i ai granules secretorty.O suʻesuʻega talu ai nei ua faʻaalia ai foi e mafai ona faʻaleleia lelei le tulaga o le anti-oxidant ma le vasodilation o le nitric oxide-mediated i le maʻisuka ituaiga 2 ma puipuia sela beta pancreatic mai le faaleagaina e le hydrogen peroxide.

fa'aoga ma fua

ose vaila'au o le hypoglycemic oral e fa'aaogaina e togafitia ai le ma'i suka e le fa'alagolago i le inisalini.Togafitiga o le ma'isuka e feso'ota'i ma le puta po'o le fa'ama'i toto, mo tagata matutua e maua i le ma'isuka ituaiga 2. O le ma'isuka ose tulaga fa'alesoifua maloloina tumau (umi) e a'afia ai le suiga o lou tino. meaai i le malosi.fa'aitiitia le maualuga o le kulukose o le toto e ala i le fa'aosofiaina o le fa'aosoina o le inisalini mai sela β o motu o Langerhans.